Sobre o curso

The Graduate Program in Environmental and Experimental Pathology - UNIP Veterinary Medicine Graduate Program had its venue in 2003, offering a Master Degree in Veterinary Immunopathology under the direction of Prof. Dr. Maurício Garcia. After two years, Prof. Dr. Mario Mariano assumed the position. The evolution and consolidation of the Program were recognized by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, CAPES, conceding the recommendation of the Doctorate in Immunopathology on 08/06/2008. 

The origin of diseases and their consequences to the animal and human health, focusing on the environment, is achieved under the light of the One World, One Health philosophy, essential to Brazil, the country with the richest biodiversity on the planet and one of the leading exporters of animal protein and grains. Due to these particularities, Brazil is considered a Hot Spot of Emerging Infectious Diseases, mainly because agriculture advances towards the forest, enabling contact with species that transmit various infections. The current COVID-19 pandemic is the most evident example of the devastating potential of new host-parasite interactions. It exposes the need for a deeper understanding of the relationships between different animal species and the environment.

The recent challenges reported to the Veterinary area in Brazil combined with UNIP’s heterogeneous and multidisciplinary profile resulted in the alteration of the Program's name to Environmental and Experimental Pathology, or GP-EEP, in February 2012.

In 2019, Prof. Dr. Maria Anete Lallo, deputy coordinator since 2011, was indicated as the course coordinator after Prof. Dr. Mario Mariano passed away and continued to lead the group according to the philosophy implemented by the late academics.

The research fields of the GP-EEP were updated in 2018, after a readjustment of the fundamentals of the Master’s and Doctoral courses, to provide better adherence to the current needs of the Veterinary Medicine area.

Dean: Sandra Rejane Gomes Miessa
Vice-Dean Office of Graduate Studies and Research: Prof. Dr. Marina da Camino Ancona Lopez Soligo
Research and Graduate Studies Coordination: Prof. Dr. Marina da Camino Ancona Lopez Soligo
Coordination: Prof. Dr. Maria Anete Lallo
Vice-Coordination: Prof. Dr. Ivana Barbosa Suffredini
Secretariat: Cecília Matos
Telephone: +55 11 5586-4171
E-mail: pgveterinaria@unip.br

The Program

A graduate student in the GP-EEP has formation in different areas of the Health, Agrarian, and Biological Sciences, which allows a multidisciplinary training that supports the development of a critical, current, innovative, and humanistic formation in the area of Environmental and Experimental Pathology under the light of the constant social demands. The interdisciplinary profile of the Collegiate and students, together with the development of basic and applied research, allows the translation of scientific knowledge to a critical and transversal view to find solutions to problems related to One Health.

Audience

Professionals trained in Health, Agrarian, and Biological Sciences, such as veterinarians, nurses, biomedical doctors, pharmacists, physiotherapists, physical education professionals, biologists, chemists, physicians, nutritionists, and related fields. 

Assessment Area: Veterinary Medicine

Area of Concentration

Environmental and Experimental Pathology
Involves the ecological study of diseases, focusing on the concepts of environmental health and One Health. The elements that potentially affect health and diseases caused by pathogens and xenobiotics introduced into the environment by human action are considered. The studies developed aim to expand knowledge and understand not only the diagnosis of pathological conditions that involve interaction with the environment, but also the search for models of corrective or mitigating interventions, contributing to the sustainability of the planet.

Research Lines

Integrated and Translational Pathology
The basis of the research developed in this line is based on the One World - One Medicine - One Health approach, which integrates environmental, human and animal factors in the context of One Health. Experimental and clinical research is aimed at understanding the pathophysiology and treatment of diseases and disorders related to environmental factors, including:

• neurodegenerative diseases caused by stress, toxic agents, pharmacological, nutritional or biological factors, as well as mental disorders;
• neglected infectious diseases, emerging diseases or those associated with variations in immunocompetence;
• neoplastic diseases.

Ecotoxicology and Therapeutic Innovations
This line of research includes studies on the evolution of diseases and disorders in different animal species, resulting from anthropogenic interference in nature, especially through exposure to toxic agents. It also includes the evaluation of substances that affect the neuro-immune-endocrine axis, using experimental and behavioral models.
The research investigates sustainable therapeutic solutions for these and other problems of human and veterinary relevance, under the One Health approach, focusing on the use of plant extracts from plants, especially those native to the Atlantic Forest and the Amazon, Brazilian biomes with a high degree of biodiversity.
In addition, the line includes the use of new drugs and the elucidation of the mechanisms of action of dynamized inputs or highly diluted homeopathic products, applied in Brazilian agriculture and in other countries.

The aims of the GP-EEP are based on the excellence of scientific development and the training of qualified personnel focusing on solving current and years-to-come problems concerning the Veterinary Medicine area. New scientific knowledge that results in social and economic benefits is the approach pursued by our students. Moreover, the improvement of teaching skills and research methodologies expands knowledge, making technological innovation possible. The achievement of didactic-scientific articulation for undergraduate, middle, and elementary school teaching and its integration with graduation program awakes vocations and talents for scientific production in the future.

In addition, the GP-EEP provides the students the integration of UNIP with the local community in a cooperative relationship that benefits both the productive and the social sectors. 

High-qualified professionals who graduate from GP-EEP can propagate high standard teaching and research performance in different fields, including national and international partnerships, exchanges with other academic institutions, and initiatives in the public and third sectors.

Mission

To offer complete education to Health, Agrarian, and Biological Sciences teachers and researchers, allowing for multidisciplinary training. Allow the generation of knowledge in a critical, current, innovative, and humanistic way in the field of Environmental and Experimental Pathology, under the light of the constant demands of the society.

Vision

Consolidate the EEP program and the participation of UNIP in the scope of national and international research concerning One Health until 2025. 

Organizational Values

They are: Ethics, inclusion, innovation, creativity, sustainability, environmental responsibility, transparency, self-criticism, solidarity, and national and international cooperation.

 

The University Master’s and Doctoral programs aim to develop studies and research that result in the production of knowledge that contributes to scientific advancement and improves the quality of life in the country and the world. The development of the GPs is based on innovation, transformation, and excellence, guided by two main axes:

1. Generation of new scientific knowledge that results in social and economic benefits;
2. Improvement of teaching, with the development of new methodologies, didactic-scientific articulation for undergraduate, secondary, and elementary schools;

Research development to expand knowledge and technological innovation; Promote integration with graduation to awaken vocations and talents for scientific production; Promote the integration of UNIP with the local community, articulating economic and the social sector in a cooperative manner, through the training of qualified professionals for teaching; high-level research, and professional performance; Establishment of national and international partnerships and exchanges with other academic institutions, business, public and third sectors, that allows continuous updating of research and postgraduate program; Identifying areas of interest and institutional vocation to create coherent, articulated, and innovative lines of research.

The University began its Post-Graduation history back in 1998 by implementing two Master’s Programs in Dentistry and Production Engineering. In 2002, two new programs were created, the Environmental and Experimental Pathology and the Communication Programs, and finally, in 2005, the Administration Program. Following the consolidation of the Master’s Programs, Doctorates in Production Engineering (2006), Environmental and Experimental Pathology (2008), Communication (2012), and Dentistry (2015) were established and reflect how compromised the University is in supporting graduate education and research.

The University research policy provides the necessary conditions for qualified scientific production aimed at the local, regional, and national demands. The Institution considers that scientific knowledge is the main asset for the sustainable and responsible economic development of a region and contributes to the training of professionals capable of proposing necessary solutions for social transformations, which include(s):

• Supporting the creation of research groups formed by internal and external professors;
• Establishing constant mechanisms for qualification and training of the Collegiate;
• Developing mechanisms for promoting the interaction with the social and business communities and funding agencies;
• Creating national and international agreements and exchanges with public and private institutions, research institutes, companies, and other institutions to develop joint projects.

The GP-EEP has a multidisciplinary and multi-professional nature, evidenced by students and professors from different areas as Veterinary Medicine, Medicine, Biology, Biomedicine, Nutrition, Physiotherapy, Dentistry, and Pharmacy. The GP-EEP strategic design is based on the research/educational strategies of the UNIP (2018-2027), and the goals established for the period 2020-2025 are highlighted below:

1. Increase the visibility/solidarity and social inclusion of the GP-EEP using digital media

Justification

Digital media plays a fundamental role in expanding the social and educational impact of the content produced in the academic environment by allowing for extramural dissemination of knowledge and allowing for the approximation with other national postgraduate programs. In this context, increased visibility strengthens transparency in research and inclusion.

Actions

• Create the Visibility/Solidarity Commission to determine actions that allow the increment of visibility of the EEP.

2. Foment the exchange of international experience

Justification

Meeting global demands that encourage the exchange of information by researchers at a global level, the collaboration of internal students and external projects provide interdisciplinary projects with the possibility of creating national and international research networks, generating publications with more significant impact, and increasing visibility.

Actions

• Encourage student participation in international events;
• Encourage Double Degree Ph.D.s;
• Increase the number of courses ministered in foreign languages;
• Actively seek the participation of international students in our program and the participation of our students in international internships;
• Encourage bilateral Visiting Professor Programs;
• Seek scholarships for internationalization.

3. Strengthening of evaluations for diagnosis and problem solving/improvements

Justification

The management of the Graduate Program in a multidimensional environment requires the improvement of self-evaluation. In this sense, the implementation of self-assessment systems involving all EEP participants enables identifiying strengths and weaknesses. External reviewers will be invited to evaluate the program, avoiding endogeny.

Actions

• Strengthen the Self-Evaluation Committee;
• Strengthen the self-evaluation instruments;
• Invite reviewers ad hoc to promote the independent evaluation of the EEP.

The Environmental and Experimental Pathology Program has modernized laboratories and accessible infrastructure for People with Special Needs (PwSN), integrated with the Research and Technology Center (CPT) and the Biodiversity Research Center (NPBio). These spaces serve not only Graduate programs but also support Undergraduate activities, including scientific initiation and internships, while also hosting students and faculty from other national and international universities.

The CPT and NPBio operate at a new location in the Indianópolis Campus, sharing a combined area of approximately 1,070 m² that includes various laboratories, faculty and student rooms, a classroom, cafeteria, and rest area.

Research and Technology Center (CPT) includes:

1. Pathological Anatomy Laboratory

   Specialized in histological processing, including histochemical and immunohistochemical techniques, working with biopsy, necropsy, or experimental materials.

2. Experimental Homeopathy Study Laboratory

   Dedicated to basic research on dynamized inputs, including biological models with Artemia salina and automated production of homeopathic potencies from raw materials approved by ANVISA or MAPA.

3. Molecular and Cellular Biology Laboratory (biosafety level 2)

   Designed for advanced research in molecular and cellular biology, supporting techniques like nucleic acid amplification (PCR), gene expression analysis, and microbial cultivation.

   Equipment: Laminar flow hoods, thermocyclers, CO2 incubators, refrigerated centrifuges, ELISA readers, BOD incubators, microscopes.

   More information here

4. Cell Culture Laboratory

   Dedicated to cell cultivation and analysis, divided into two rooms: one for non-infected cells and another for pathogen-exposed cells.

   Equipment: Laminar flow hood, centrifuge, CO2 incubator, inverted microscope.

   More information here

5. Cryopreservation Laboratory

   For safe preservation of biological materials used in scientific research.

   Equipment: Two ultra-low freezers (-80°C), three liquid nitrogen tanks (-196°C).

6. Imaging Laboratory

   For fluorescence microscopy, bright-field microscopy, and digital macroscopy records.

   Equipment: Specialized microscopy equipment.

7. Flow Cytometry Laboratory

   Specialized in multiparametric analysis of suspended cells for immunophenotyping, apoptosis studies, and biomarker detection.

   Equipment: BD Accuri C6 flow cytometer.

   More information here

8. SPF Animal Facility and Fish Bioterium

   Maintains rats, mice and zebrafish (Danio rerio) under Specific Pathogen Free conditions, with specialized rooms for surgery, necropsy, and ultrasonic vocalization studies.

   Equipment: Techniplast microisolators, Noldus-EthoVision system, surgical equipment.

   More information here

Biodiversity Research Center (NPBio) includes:

1. Herbarium

   Officially registered as "HERBÁRIO UNIP" with the Brazilian Botanical Society, containing about 11,000 Amazonian plant specimens.

   More information here

2. Extraction Laboratory and Extract Library

   Stores over 2,300 extracts from Amazonian, Atlantic Forest and Antarctic plants at -20°C.

   More information here

3. Microbiology Laboratory

   Evaluates antimicrobial response of plant extracts against veterinary-relevant bacteria and fungi.

4. Antitumor Screening Laboratory

   Assesses cytotoxic activity of extracts against malignant tumors cultured in vitro, following NCI standards.

   Funding: Partially funded by FAPESP (2019/12202-3, 2018/21278-0, 2017/03470-9).

Infrastructure and Team

The multi-user laboratories are supported by 8 dedicated staff members including lab managers, herbarium curator, and technicians who provide training, maintenance, and experimental support. Veterinary hospitals at UNIP's Anchieta, Campinas, Bauru and São José dos Campos campuses support PPG-PAE research, along with partnerships with Butantan Institute, UNIFESP, USP and others.

University Structure

UNIP provides modern infrastructure supporting graduate activities including:

1. Theory and seminar rooms: Air-conditioned with computers, multimedia projectors, and hybrid videoconferencing via Microsoft Teams.

2. Qualification and defense rooms: Two equipped rooms with videoconferencing capabilities.

3. Student and faculty rooms: With computers, high-speed internet and printing facilities.

4. Auditoriums: With capacities for 50, 150 and 600 people.

5. Graduate Studies Office: Administrative support for students and faculty.

6. Library: The Indianópolis Library offers specialized team, accessible infrastructure, and access to 1,720,314 volumes and online databases through CAPES Portal.

7. Computer labs: Equipped with 20 computers, printers, and statistical analysis software.

1. Prof. Dr. Anuska Marcelino Alvares-Saraiva
   a) Partnership: Prof. Dr. Rui Curi - Institute of Physical Activity and Sport Sciences - ICAFE / Cruzeiro do Sul University, Sao Paulo; Dr Sandra Coccuzzo Sampaio Vessoni - Pathophysiology Laboratory of the Butantan Institute, Sao Paulo and Dr. Diva Denelle Spadacci-Morena - Pathophysiology Laboratory of the Butantan Institute, Sao Paulo. Project involved: Insulin-producing B-1 lymphocytes as a therapeutic target in Type 1 Diabetes: In vitro and in vivo study
   b) Partnership: Prof. Dr. Rui Curi, Prof. Dr. Tania Cristina Pithon Curi, Prof. Dr. Renata Gorjao and Prof. Dr. Sandro Massao Hirabara - Institute of Physical Activity and Sport Sciences - ICAFE / Cruzeiro do Sul University, Sao Paulo. Project involved: Cellular and molecular mechanisms involved in insulin resistance and inflammation in obese Wistar and goto-kakizaki lean rats: Causes and associations with diet and exercise
   c) Partnership: Prof. Dr. Ronni Rômulo Novaes e Brito – Sao Camilo University Center, Sao Paulo and Prof. Dr. Patrícia Xander Batista - Institute of Environmental, Chemical and Pharmaceutical Sciences (ICAQF)/ Federal University of Sao Paulo, Campus Diadema. Project involved: Behavior of B-1 cells in mice subjected to sleep restriction

2. Prof. Dr. Eduardo Fernandes Bondan
   a) Partnership: Prof. Dr. Rosemari Otton - Laboratory of Natural Antioxidants - Cruzeiro do Sul University (Sao Paulo - SP). Project involved: Study of the morphological, oxidative and behavioral effects of the administration of doxorubicin associated with curcumin and resveratrol in Wistar rats
   b) Partnership: Transmission Electron Microscopy Laboratory, Department of Anatomy, Faculty of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ – USP). Project involved: Ultrastructural study of glial cells Bothrops jararaca (Reptilia, Ofidia)
   c) Partnership: Dr. Marcelo Paes de Barros (Institute of Physical Activity and Sport Sciences - ICAFE / Cruzeiro do Sul University). Project involved: Study of oxidative parameters in the central nervous system of rats treated with doxorubicin
   d) Partnership: Dr. Miriam Oliveira Ribeiro (Laboratory of Neurobiology / Universidade Presbiteriana Mackenzie). Project involved: Induction of iodothyronine deiodinase after status epilepticus modifies hippocampal gene expression in male mice

3. Prof. Dr. Elizabeth Cristina Pérez Hurtado
   a) Partnership: Drs. Patricia Xander and Ana Claudia Torrecilhas. Department of Microbiology, Immunology and Parasitology Federal University of Sao Paulo and Institute of Environmental, Chemical and Pharmaceutical Sciences (ICAQF) Federal University of Sao Paulo, Campus Diadema. Project involved: In vivo evaluation of the influence of extracellular vesicles released by 4T1 cells on breast tumor development.
   b) Partnership: Prof. Dr. Diva Denelle Spadacci-Morena. Pathophysiology Laboratory, Instituto Butanta and Center for Biological and Health Sciences, Universidade Cruzeiro do Sul. Project involved: In vitro evaluation of the influence of extracellular vesicles released by melanoma cells on the metabolism of murine macrophages.
   c) Partnership: Prof. Dr. Ivone Mackowiak. Department of Pathology - FMVZ- USP. Project involved: In vitro evaluation of the effect of homeopathic preparations Phytolacca decandra on human breast adenocarcinoma cells.
   d) Partnership: Prof. Dr. Mario Cruz. Research Support Facility Center (CEFAP-USP). Project involved:study In vitro of the expression and epigenetic regulation of M-SEC protein in breast adenocarcinoma cells, after interactions with macrophages.
   e) Partnership: Prof. Dr. Carla Holandino. Faculty of Pharmacy, Federal University of Rio de Janeiro (UFRJ). Projects involved: 1.evaluation In vitro of the effect of homeopathic preparations Viscum album on murine melanoma cells (B16F10). 2. Study of the effects in vivo of homeopathic preparations of Viscum album (L.) in the murine melanoma model

4. Prof. Dr. Ivana Barbosa Suffredini
   a) Partnership: Prof. Dr. Joao Henrique Ghilardi Lago – Center for Natural and Human Sciences – UFABC. Project involved: Screening of plant extracts with antifungal activity.
   b) Partnerships: Prof. Dr. Márcia Ortiz M. Marques – Agronomic Institute of Campinas; Prof. Dr. Marcos N. Eberlin – ThomSon Laboratory, UNICAMP Institute of Chemistry and UP Mackenzie. Project involved: Evaluation of essential oil components of Iryanthera polyneura.
   c) Partnerships: Prof. Dr. Jorge Flório – Veterinary Medicine USP; Prof. Dr. Cidéli P. Coelho – Santo Amaro University. Project involved: Study of behavioral changes in Luffa operculata in Wistar rats
   d) Partnerships: Prof. Dr. Paulo RH Moreno – Institute of Chemistry at USP. Project involved: Alkaloids and biological activities of Annona hypoglauca.
   e) Partnerships: Prof. Dr. Luiz Fernando L. Reis – Hospital Sírio Libanes; Prof. Dr. Riad N. Younes – Oswaldo Cruz German Hospital. Project involved: Chemical and biological study of Microplumeria anomalous.
   f) Partnerships: Prof. Dr. Cintia HC Saraceni, Prof. Dr. Maristela Dutra-Correia, Prof. Dr. Maristela Dutra-Correia. Dr. Luciano Dib, Prof. Dr. Élcio M. Giovani – PPG-Dentistry UNIP. Projects involved: Bacterial and biofilm analysis in dental materials.

5. Prof. Dr. José Guilherme Xavier
   a) Partnership: Prof. Dr. Cristina de O. Massoco S. Gomes – Department of Pathology – FMVZ-USP. Project involved: Microenvironment and tumor aggressiveness: cancer-associated fibroblasts (CAFs), pericytes and prognosis in canine oral melanoma
   b) Partnership: Prof. Dr. Ricardo de Francisco Strefezzi, Department of Veterinary Medicine, Faculty of Animal Science and Food Engineering-USP. Projects involved: Tumor-extracellular matrix interaction in canine cutaneous mast cell tumors; Characterization of genes related to apoptosis in canine cutaneous mast cell tumors and their value as a prognostic indicator
   c) Partnership: Prof. Dr. Primavera Borelli – Department of Clinical and Toxicological Analysis at FCF-USP. Projects involved: Evaluation of the hematopoietic endosteal niche of mice subjected to protein malnutrition

6. Prof. Dr. Leoni V. Bonamin
   a) Partnership: Prof. Joao Sarkis Yunes, FURGS, RS, Brazil; Prof. Igor Jerman - Bion Institute, Slovenia; Prof. Steven Cartwright - Diagnox, Oxford, UK. Project involved: Effects of isotherapeutics on the experimental intoxication of Artemia salina
   b) Partnership: Prof. Carla Holandino - Federal University of Rio de Janeiro; Prof. Steven Cartwright - Diagnox, Oxford, UK. Project involved: Physicochemical characterization of homeopathic medicines.
   c) Partnership: Prof. Silvia Waisse - Pontifical Catholic University of Sao Paulo. Project involved: International book publishing: Transdisciplinarity and Translationality in High Dilutions Research - Signal and Image GIRI series. Cambridge Scholars Publishing, Cambridge, UK. 2019.
   d) Partnership: Dr. Sergio Ribeiro - CIRAT / IPWS (International Panel on Water Structure), Brasilia, Brazil; Prof. Gerald Pollack, University of Washington in Seattle, USA. Project involved: Editing of a special issue of the journal Water - A multidisciplinary research journal - Commemorative edition for the 9th World Water Forum in Dakar, March 2022, with the objective of disseminating advanced knowledge about water at different structural levels.

7. Prof. Dr. Maria Anete Lallo
   a) Partnership: Instituto Butantan, Laboratory of Physiopathology, to perform transmission electron microscopy, Dr. Diva Denelle Spadacci-Morena. Project involved: Morphodifferentiation of the Organ of Gene of engorged ticks Amblyomma sculptum (Acari: Ixodidae)
   b) Partnership: Disciplines of Cell Biology and Immunology, Department of Microbiology and Immunology – Federal University of Sao Paulo, Prof. Dr. Alexandre Keller. Project involved: Role of NKT cells in encephalitozoonosis
   c) Partnership: Department of Micro, Immuno-Parasitology Federal University of Sao Paulo and Institute of Environmental, Chemical and Pharmaceutical Sciences (ICAQF) Federal University of Sao Paulo campus Diadema, Prof. Dr. Patricia Xander Batista. Project involved: Influence of B-1 cells or their extracellular vesicles on the activity of effector immune cells in microsporidiosis

8. Prof. Dr. Maria Martha Bernardi
   a) Partnership: Dr. Claudia Madalena Mori - Department of Pathology - FMVZ / University of Sao Paulo. Project involved: Phenotypic characterization of ENU-induced and spontaneous mutant mice
   b) Partnership: Sandra Maria Miraglia Valdeolivas - Escola Paulista de Medicina – EPM/UNIFESP Department: Morphology and Genetics. Project involved: Effects of moderate chronic stress, induced from peripuberty, and escitalopram treatment on the reproductive parameters of adult rats.
   c) Partnership: Dr. Miriam Oliveira Ribeiro (Laboratory of Neurobiology / Universidade Presbiteriana Mackenzie). Projects Involved: 1. Hyperlipidic diet increases fat weight and induces glucose intolerance in Balb-c-XID mice. 2. Role of environmental enrichment in the recovery of memory impairment in ?3-ARKO mice

9. Prof. Dr. Rodrigo Augusto da Silva
   a) Partnership: Prof. Dr. Willian Fernando Zambuzzi, LaBio – Laboratory of Bioassays and Cell Dynamics, Universidade Estadual Paulista, UNESP. Project: Osteogenic markers and epigenetic reprogramming during the phenotypic transition of vascular smooth muscle: from contraction to calcification.
   b) Partnership: Prof. Dr. Alexandra Latini, LABOX – Laboratory of Bioenergetics and Oxidative Stress, Federal University of Santa Catarina, UFSC. Project: Metabolic, biochemical and epigenetic characterization of the inflammatory response in the Central Nervous System.
   c) Partnership: Prof. Dr. Alex Rafacho, LIDoC – Chronic Disease Research Laboratory, Federal University of Santa Catarina, UFSC. Project: Impact of exposure to organophosphate pesticides on gestation, post-term, fetuses and adult offspring of rats.
   d) Partnership: Prof. Dr. Alexander Birbrair, Birbrair Lab, Federal University of Minas Gerais, UFMG. Project: Evaluation of the impact of sensory nerve activation in the modulation of epigenetic mechanisms in the tumor microenvironment: Implications for tumor development and progression.
   e) Partnership: Prof. Dr. Valério Garrone Barauna, Center for Physiological Sciences, Federal University of Espírito Santo, UFES. Project: Pathophysiological Mechanisms and the Search for Biomarkers in Septic Patients: role of cfDNA methylation. 

10. Prof. Dr. Thiago Berti Kirsten
    a) Partnership: Prof. Dr. Luciano Freitas Felicio - Laboratory of Reproductive Behavior Neurobiology, Faculty of Veterinary Medicine and Animal Science, University of Sao Paulo. Project involved: Autism and dopaminergic system - analysis of sex differences, molecular and behavioral aspects.
    b) Partnership: Prof. Dr. Claudia Madalena Mori - Laboratory of Animal Models, Faculty of Veterinary Medicine and Animal Science, University of Sao Paulo. Project involved: Studies with spontaneous and chemically induced mutant mice.
    c) Partnership: Prof. Dr. Helenice de Souza Spinosa – Department of Pathology, Faculty of Veterinary Medicine and Animal Science, University of Sao Paulo. Project involved: Exposure of dams to fluoxetine during lactation disturbs maternal behavior but had no effect on the offspring behavior.

11. Prof. Dr. Welber Senten Smith
    a) Partnership: Prof. Dr. Miguel Petrere Jr – Postgraduate Program in Aquatic Ecology and Fisheries – UFPA. Project involved: Reproductive biology of migratory fish from the Sorocaba river basin as subsidies for the maintenance of free stretches of rivers.

The self-evaluation process has guided the Program's changes since its venue in 2003 up to now. By changing the name of the research themes of the Graduate Program in Environmental and Experimental Pathology, it was possible to apply and probe the basis of the One Health concept. So, the GP_EEP goals changed due to the need to increase the quality of scientific knowledge for the Veterinary Medicine area. Thus, goals such as increasing the number and quality of projects developed, seeking internationalization, and extramural cooperation has been achieved. It has increased the program score given by CAPES to 5.0.

Today, the GP-EEP has a unique vocation, profile, and personality in Veterinary Medicine that is constantly being supported by the One World, One Health concept. The multidisciplinary Collegiate, composed of veterinarians, biologists, pharmacists, and biomedicine professionals, who have brought unique and complementary experiences and competencies to characterize the Program's profile, enables the multidisciplinarity necessary to provide the student with a training of excellence.

The current profile of the Program is closely related to the guidelines of the UNIP Institutional Development Plan (IDP), which guides its role in Brazilian Veterinary Medicine. In conjunction with the IDP - UNIP, periodic quality assessments are made with the Collegiate, student staff, and employees. Currently, the GP-EEP developed a query in the Google Forms platform, which was available to teachers, students, and employees. The aspects addressed in the questionnaire were defined by the Evaluation Committee, composed of representatives of the three categories of participants. Based on the results, the Evaluation Committee communicated to the Collegiate, which implements the improvements through its Coordinator and the Graduate General Coordination.

Download of self-evaluation graphics. PDF