Syllabus
Diagnostic tests based on the utilization of Molecular biology. Usage and objectives of the different techniques of Molecular Biology used in Dentistry. Scientific application of techniques such as Real Time PCR, DNA-DNA Checkerboard and DNA cloning. Perspectives of the use of Molecular Biology for the development of dental practice.
Bibliography
Alberts B et al. Biologia Molecular da Célula. Tradução Ana Letícia de Souza Vanz et al. 6ª ed. Porto Alegre: Artmed; 2017.
Zaha A, Ferreira HB, Passaglia L M. P. Biologia Molecular Básica. 5ª ed. Porto Alegre: Artmed; 2014.
Gupta S, Chhina S, Arora SA. A systematic review of biomarkers of gingival crevicular fluid: Their predictive role in diagnosis of periodontal disease status. J Oral Biol Craniofac Res. 2018 May-Aug;8(2):98-104.
Dabdoub SM, Tsigarida AA, Kumar PS. Patient-specific Analysis of Periodontal and Peri-implant Microbiomes. J Dent Res. 2013 Dec;92(12 Suppl):168S-75S. doi: 10.1177/0022034513504950.
Violant D, Galofré M, Nart J, Teles RP. In vitro evaluation of a multispecies oral biofilm on different implant surfaces. Biomed Mater. 2014 Jun;9(3):035007.
Kanasi E, Dewhirst FE, Chalmers NI, Kent R Jr, Moore A, Hughes CV, Pradhan N, Loo CY, Tanner AC. Clonal analysis of the microbiota of severe early childhood caries. Caries Res. 2010; 44(5):485-97.
Chaves de Souza JA, Frasnelli SC, Curylofo-Zotti FA, Ávila-Campos MJ, Spolidório LC, Zamboni DS, Graves DT, Rossa C Jr. NOD1 in the modulation of host-microbe interactions and inflammatory bone resorption in the periodontal disease model. Immunology. 2016;149(4):374-385.
Grdović N, Rajić J, Petrović SM, Dinić S, Uskoković A, Mihailović M, Jovanović JA, Tolić A, Pucar A, Milašin J, Vidaković M. Association of CXCL12 gene promoter methylation with periodontitis in patients with diabetes mellitus type 2. Arch Oral Biol. 2016;72:124-133.
Periódicos:
Journal of Periodontology
Journal of Periodontal Research
Journal of Clinical Periodontology
Periodontology 2000
International Journal of Periodontics and Restorative Dentistry